CESE is a software that provides an integrated platform for carrying out computational simulations using different electrophysiological models, making it an efficient solution that can be used for a variety of tasks.
As a software review, CESE (Cell Electrophysiology Simulation Environment) is an exceptional software that is specifically designed for computational electrophysiological simulations. It is packed with features that make it useful for simulations of action potentials, individual ionic currents, and changes in ionic concentrations. CESE is a cross-platform program, and it can run effectively on any system that has Java runtime environment (JRE) version 1.5 (5.0) or above. The software has been tested on MacOS X, Windows, Linux, Solaris, and AIX.
CESE is an integrated environment that is perfect for performing computational simulations using a variety of electrophysiological models. At its current state, the software allows for the creation and execution of the single-cell models that contain both Hodgkin-Huxley (HH) and Markovian current formulations. Furthermore, CESE comes with models of electrical activity of cardiac myocytes with source code already included in the distribution. The developers also plan to expand the software in the future by adding new models, including certain neuronal models.
One of the main strengths of this software is its uniformity - a program interface that remains the same for different types of models. You can easily switch between models and compare simulation outputs while modifying model parameters, selecting them for output, and clamping them in the same standard way. CESE extends the conventional electrophysiologic meaning of the "voltage clamp," which now allows you to clamp virtually any model variable, including voltage (membrane potential), total or individual ionic currents, ionic concentrations, temperature, gating variables, and more.
CESE provides simple but efficient data visualizations. Simulation results can be presented in graphical and tabulated forms, with plots that are customizable, and regions of interest zoomed for better analysis. Although CESE was not necessarily designed as a data analysis tool, one can still generate current-voltage relationships (I-Vs) within the program, calculate statistical parameters for a given signal, and export data to ASCII, Axon Text File (ATF), and NetCDF formats for further analysis in other software packages.
Overall, CESE is a great software for electrophysiology modeling with a user-friendly experience, diverse modeling capabilities, and data visualization tools that make it easier to analyze simulation results.
CESE is an integrated environment that is perfect for performing computational simulations using a variety of electrophysiological models. At its current state, the software allows for the creation and execution of the single-cell models that contain both Hodgkin-Huxley (HH) and Markovian current formulations. Furthermore, CESE comes with models of electrical activity of cardiac myocytes with source code already included in the distribution. The developers also plan to expand the software in the future by adding new models, including certain neuronal models.
One of the main strengths of this software is its uniformity - a program interface that remains the same for different types of models. You can easily switch between models and compare simulation outputs while modifying model parameters, selecting them for output, and clamping them in the same standard way. CESE extends the conventional electrophysiologic meaning of the "voltage clamp," which now allows you to clamp virtually any model variable, including voltage (membrane potential), total or individual ionic currents, ionic concentrations, temperature, gating variables, and more.
CESE provides simple but efficient data visualizations. Simulation results can be presented in graphical and tabulated forms, with plots that are customizable, and regions of interest zoomed for better analysis. Although CESE was not necessarily designed as a data analysis tool, one can still generate current-voltage relationships (I-Vs) within the program, calculate statistical parameters for a given signal, and export data to ASCII, Axon Text File (ATF), and NetCDF formats for further analysis in other software packages.
Overall, CESE is a great software for electrophysiology modeling with a user-friendly experience, diverse modeling capabilities, and data visualization tools that make it easier to analyze simulation results.
What's New
Version 1.4.7: N/A