D2OL software helps in discovering drugs to fight against Anthrax, Smallpox, Ebola and SARS.
D2OL runs seamlessly in the background of your computer without requiring any kind of intervention. It continues to execute as long as it is turned on, whether you are connected to the internet or not. D2OL was the pioneer in using computational methods to deploy targets against Anthrax, Smallpox, and Ebola, and now has added a credible SARS target using a conservation approach between pig and human coronavirus, the suspected virus behind SARS.
Once you download and install the D2OL software, your computer is given drug candidates to evaluate. Your computer then begins the candidate evaluation process, which is similar to finding the right key to fit into a lock. Using distributed computing technology, the software sends hundreds of thousands of possible keys to all computing devices participating in the network. The results are managed on the D2OL website and will be returned to the network once you connect again to the internet.
At D2OL, we take advantage of all available computing devices within our community, including personal computers, servers, and gaming devices like TiVo and the Xbox. Our platform is cost-effective, and it helps us combat major health concerns and potential future threats through massive, parallel computing power. We use our proprietary methodology to identify targets, focusing on epidemiology, drugability, and the target's role in the pathogen's lifecycle. We collaborate with experts in computational chemistry and structure-based drug design to improve our society's response to these ever-increasing threats.
The D2OL software requires Java 1.4.1 to run. Overall, D2OL is an excellent software application that allows users to contribute to combatting dangerous infectious diseases using their unused processing power. The application is user-friendly, non-intrusive and requires minimal intervention.
Version 3.0: N/A