Refmac is a powerful macromolecular refinement program that can perform rigid body, tls and refinement against X-ray data, ideal for structural biology researchers.
The REFMAC program is a versatile refinement software that offers a range of options for refining macromolecular structures against X-ray data. It can carry out rigid body, tls, restrained or unrestrained refinement, as well as idealisation of the structure.
The program utilises coordinate parameters and minimises them to achieve a satisfactory residual, with the option of using either the Maximum Likelihood or Least Squares method. Additionally, REFMAC offers different methods for minimisation, although at present only CGMAT is active.
One of the advantages of REFMAC is its ability to create MTZ output files, which allow the user to store weighted coefficients for 2mFo-DFcalc maps and SigmaA weighted mFo-DFcalc. These files are particularly useful for storing data where "missing data" have been moved.
Overall, REFMAC is a valuable resource for researchers working with macromolecular structures, thanks to its versatile refining capabilities and MTZ output file creation.
The program utilises coordinate parameters and minimises them to achieve a satisfactory residual, with the option of using either the Maximum Likelihood or Least Squares method. Additionally, REFMAC offers different methods for minimisation, although at present only CGMAT is active.
One of the advantages of REFMAC is its ability to create MTZ output files, which allow the user to store weighted coefficients for 2mFo-DFcalc maps and SigmaA weighted mFo-DFcalc. These files are particularly useful for storing data where "missing data" have been moved.
Overall, REFMAC is a valuable resource for researchers working with macromolecular structures, thanks to its versatile refining capabilities and MTZ output file creation.
What's New
Version 5.4: N/A