Genomorama is a versatile genome visualization and analysis software that can handle multiple genomes, platforms, and scales.
Genomorama is a high-performance system that has not been sacrificed on the altar of portability. It leverages OpenGL graphics to advantage of the video-game optimized graphics cards available in most desktop and laptop computers. Additionally, C++ allows transparent and complete utilization of system resources (like memory). The software also features native windowing toolkits (Carbon, MFC, and Motif) for every operating system to facilitate responsiveness and ease of use. The program is a stand-alone, self-contained executable, which increases its efficiency and independence from dependence on third-party applications. Moreover, source code for all platforms is freely provided.
Genomorama's user interface is attractive and full-featured, depicting a clean, uncluttered user interface. Multi-scale rendering displays relevant details while maintaining readability. Efficiently zoom, pan and explore genomes of arbitrary sizes can be done using a keyboard or mouse. When it comes to output, the software provides attractive WYSIWYG Postscript and GIF output formats that yield high-quality publication images.
One of Genomorama's key innovative features is its ability to assist genome analysis significantly. It offers a DNS hybridization based search based on forward and reverse pairs. Additionally, provide a pair of PCR primers and Genomorama outputs the amplicons, provide a hybridization probe, and Genomorama finds binding sites. The software also incorporates a feature that finds a pair of Padlock probes to locate binding locations, and provide PCR primer criteria, and Genomorama finds PCR primers. The software can display and search an arbitrary number of genomes, limited only by computer memory. Harness the power of the NCBI toolkit to directly access and search the NCBI Entrez database. The software can also compute melting profile, in addition to traditional base composition plots (i.e. %G+C, %A+T, etc.).
In the latest release, Genomorama has fixed several bugs, such as parsing gbk files containing single base annotations on the complement strand, missed exact matches at 3' end of the target sequence, fragile parsing of annotation range, and downloading of very large Genbank records, i.e., human chromosomes. Additionally, custom color records are now saved to and read from GBK files. There is now an OS X Intel-specific executable, and the information dialog box is now resizable.
Overall, Genomorama Genome Visualization is a powerful yet user-friendly software that provides a robust analysis and visualization solution, making it an ideal choice for any genome analysis and visualization needs.
Version 1.5: N/A