Single Marker Association is a user-friendly tool for SNP marker analysis, providing calculations of individual marker associations.
To use the Single Marker Association tool, two files are required as input: the first file is a set of case haplotypes and the second file is a set of control haplotypes. The format of the files should be one line per haplotype, where the SNP data is represented as 0 or 1 and separated by white-space.
The installation process for SMA is straightforward. The tool is written in C++ and should compile on Unix-like systems. To install SMA, simply download the source code and unpack it using the command "tar xzf sma-v.tar.gz," where "v" is the version number of sma. Once unpacked, run "make" in the subdirectory sma-v created during unpacking.
The latest release of the Single Marker Association tool includes support for (unphased) genotype data. Overall, this software tool is a simple yet effective way to calculate the single marker association between individual SNP markers and a case/control dichotomy.
Version 2.0: N/A