ThermonucleotideBLAST is a tool that helps to find specific nucleic acid sequences in a given database. It can be used for fast and accurate searches in genetic research and analysis.
Unlike other software programs available on the market - like BLAST - ThermonucleotideBLAST goes beyond the use of heuristic sequence similarity measures when identifying matches between query and target sequences. Instead, the tool uses free energy and melting temperature, which are highly accurate methods for analyzing nucleic acid sequences.
One of the best things about this update is the significant rewrite of the thermodynamic alignment algorithm. The update includes the addition of the Dinkelbach fractional programming algorithm, which makes computing duplex melting temperatures even faster and more efficient.
Overall, ThermonucleotideBLAST is a highly reliable and user-friendly software that allows you to quickly and accurately search for nucleic acid sequences. Whether you're a seasoned bioinformatician or a beginner in this field, this tool is an excellent choice.
Version 1.05: N/A