SigInt is a software tool that helps identify and rank mammalian proteins and genes. It operates on the command line and can be useful in various research projects.
If you’re looking for a powerful software tool that can help you find and rank mammalian proteins or genes, then SigInt could be the perfect solution. Designed to work as a command-line tool, SigInt is capable of detecting proteins/genes that interact with a selection of proteins/genes within the context of a larger mammalian signalome and interactome network.
The program is surprisingly easy to use, with the inputs being limited to a seed list of human Entrez Gene gene symbols, a background network in SIG format, and a name for the output file (which is a web-page file with the htm extension). Once you have your inputs organized, SigInt will provide you with a sorted list of genes/proteins that interact with the components from your seed list. These components are ranked by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.
One of the best aspects of SigInt is its flexibility. The program can be run on a range of different operating systems, including Linux, Mac, and Windows. Plus, all it requires is a background network text file in SIG format, making it a great choice for scientists or researchers working across different platforms.
Overall, SigInt provides a powerful and reliable software tool for identifying and ranking mammalian proteins and genes. It is easy to use, highly flexible, and gives reliable results time and time again. If you’re looking for software that can help you make the most of your mammalian signalome and interactome network data, then SigInt could well be worth checking out.
The program is surprisingly easy to use, with the inputs being limited to a seed list of human Entrez Gene gene symbols, a background network in SIG format, and a name for the output file (which is a web-page file with the htm extension). Once you have your inputs organized, SigInt will provide you with a sorted list of genes/proteins that interact with the components from your seed list. These components are ranked by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.
One of the best aspects of SigInt is its flexibility. The program can be run on a range of different operating systems, including Linux, Mac, and Windows. Plus, all it requires is a background network text file in SIG format, making it a great choice for scientists or researchers working across different platforms.
Overall, SigInt provides a powerful and reliable software tool for identifying and ranking mammalian proteins and genes. It is easy to use, highly flexible, and gives reliable results time and time again. If you’re looking for software that can help you make the most of your mammalian signalome and interactome network data, then SigInt could well be worth checking out.
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