This software utilizes gene predictions, protein and transcript alignments to create accurate and weighted consensus gene structures.
The EVM software is an essential component of the eukaryotic automated gene structure annotation pipeline used at The Institute for Genomic Research. To use EVM, one needs to input the genome sequence, gene predictions and alignment data in GFF3 format, and a list of numeric weight values, which can be configured manually or trained for optimal performance using the included training software.
EVM makes it easy to combine a diverse range of evidence types, including transcript evidence, protein homology, and ab initio gene predictions, into a single, reliable gene structure annotation system. With its intuitive user interface, the software offers a seamless experience for researchers working on genomic annotations.
Overall, EVM offers a powerful gene structure annotation system that combines multiple sources of evidence to produce a high-quality annotation. Its ability to automatically weigh evidences proves to be very useful, and manual configuration makes it even more efficient.
Version 04102009: N/A